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Managing Director: Karl Richter · Control: Bio-Gate AG · Control: Bio-Gate AG Hrb4 Aug 2016 German Trade Register Announcements, Germany (03/08/2016)

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HRB 21298: BioEpiderm GmbH, Ungenannte Str. ??, 90411 Nürnberg, Germany. Changed power of representation, now: Managing Director: Richter, Karl, Windsor/ Canada, *??.??.????, authorized to represent one person; with the power to enter into legal transactions on behalf of the company in its own name or as a representative of a third party. On June 9, 2016, the company entered into a control and profit transfer agreement with the Bio-Gate AG with its registered office in Nuremberg (District Court of Nuremberg HRB 22271) a.s. the dominant company. The Shareholders' Meeting approved by resolution of June 9, 2016.

This filing was translated from German to English. The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: BioEpiderm GmbH, Nuremberg, Germany.

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