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EU funding (€2,677,118): GLYCOprotein N-glycosylation from non-life to eukaryotes: a Doctoral Network to expand the knowledge on a ubiquitous posttranslational modification of proteins Hor24 Jul 2023 EU Research and Innovation programme "Horizon"
Overview
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GLYCOprotein N-glycosylation from non-life to eukaryotes: a Doctoral Network to expand the knowledge on a ubiquitous posttranslational modification of proteins
The GLYCO-N training network aims at training Doctoral Candidates (DCs) to acquire the skills to develop different innovative strategies to 1) understand the diversity and structural complexity of archaeal, microalgal and viral N-glycosylation and 2) harness this knowledge for new solutions in biomedicine and biotechnology. Protein N-glycosylation, or the attachment of oligo- and polysaccharides at specific asparagine residues, is conserved throughout life, and is now observed even in the viral world. In contrast to eukaryotes, whose well-studied N-glycosylation machineries are relatively simple, archaea, microalgae and bacteria utilize a wide variety of monosaccharides to create a wealth of structurally diverse N-glycans, and the same holds true for some recently discovered viruses. Because protein glycosylation occurs far downstream of protein synthesis the complexity and diversity in N-glycan structures are poorly understood in detail. This holds true specifically for N-glycosylation events that are the subject of the GLYCO-N program: those in archaea, microalgae and viruses. Understanding of the how and why of N-glycosylation in archaea, microalgae and viruses will open up many possibilities ranging from drug discovery (antivirals) to biotechnology (glycoprotein and glycoprocessing enzyme engineering for materials and life sciences). The GLYCO-N network brings together a diverse group of glycobiology researchers with world-leading expertise in microbiology, (bio)organic chemistry, computational and structural biology, bioinformatics and chemical biology. The GLYCO-N DCs will have their own individual project with one GLYCO-N expert and will, through research internships, be exposed to complementary Glycoscience. All individual PhD projects, while rooted in fundamental science, have a practical application, either in biotechnology or in biomedicine, as will be explored through secondments with our associated partners.
Funded Companies:
| Company name | Funding amount |
| Adaptam Therapeutics SL | ? |
| Asociacion Centro de Investigacion CRL en Biociencias | €251,971 |
| Danmarks Tekniske Universitet | €301,788 |
| Universita Degli Studi Di Napoli Federico II | €518,875 |
| UNIVERSITAET DUISBURG-ESSEN | €521,078 |
| Universitat de Barcelona | €251,971 |
| Universite de Rouen Normandie | €282,694 |
| UNIVERSITEIT LEIDEN | €548,741 |
Source: https://cordis.europa.eu/project/id/101119499
The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: Adaptam Therapeutics SL, Donostia, Spain.
