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UK funding (£371,731): Development Clinical Studies - fMRI-based neurofeedback as a treatment tool for depression Ukri8 Feb 2012 UK Research and Innovation, United Kingdom

Overview

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Development Clinical Studies - fMRI-based neurofeedback as a treatment tool for depression

Abstract Depression is the second most common illness in primary health care and disrupts the everyday functioning of over 100 million people worldwide. Depression is a severe mood disorder that is characterised by clinical features such as anhedonia (a loss of pleasure in previously enjoyable activities), cognitive and emotional impairment, psychomotor retardation, and disturbances in sleep and appetite. 20-40% of all patients do not benefit from traditional treatment methods such as psychotherapy or anti-depressant medication. This project will investigate a potential new treatment method: functional magnetic resonance imaging (fMRI)-based neurofeedback. In this method people undergo fMRI-scanning and receive continuously updated feedback about the activity level in a certain brain area, which they use to learn to control their own brain activity. It has previously been shown that chronic pain patients experienced considerably less pain after exercising control over a brain area involved in pain processing. In our project feedback from a region involved in positive emotion processing will be provided so that depressed patients can learn to regulate their emotional state. A pilot study of this method from our group has shown that depressed patients are both able to regulate their emotional network and experience significant improvements in mood.
Category Research Grant
Reference G1100629/1
Status Closed
Funded period start 08/02/2012
Funded period end 07/02/2015
Funded value £371,731.00
Source https://gtr.ukri.org/projects?ref=G1100629%2F1

Participating Organisations

CARDIFF UNIVERSITY

The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: Cardiff University, Cardiff.