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EU funding (€4,998,433): Pan-Africa network for genomic surveillance of poverty related diseases and emerging pathogens Hor1 Jul 2023 EU Research and Innovation programme "Horizon"

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Pan-Africa network for genomic surveillance of poverty related diseases and emerging pathogens

The main aim of the proposed project is to use genomic epidemiology of tuberculosis, malaria and emerging and re-emerging pathogens in Africa as to better understand disease etiology, dynamics of disease transmission, and evolution of drug-resistant pathogens. The study also aims to increase Africa's capacity in bioinformatics, genomics, genomics data management, biobanking, and promote data sharing. Our goal is to improve the health of Africans with innovations in disease surveillance, equip the next generation of African scientists with cutting edge skills and strengthening south-south research collaborations. We propose the following hypotheses: 1. Increased capacity in genomic epidemiology will enable more effective disease surveillance in Africa. 2. Increased capacity in biobanking and genomics data management and analysis in Africa will enhance regional surveillance of infectious diseases and encourage timely and effective responses to emerging pathogens. 3. Regional whole genome sequence-based surveillance will improve the detection of DR-TB and inform the development of more sensitive and specific rapid diagnostics for the detection and surveillance of DR-TB in Africa and elsewhere. 4. Regional genomic surveillance of malaria parasites will inform a pre-emptive detection of emerging DR parasites and measure the impact of programmatic interventions for a data driven decision making by policy makers. 5. Implementation of harmonized genomic data analysis tools will allow the creation of continent-wide surveillance networks able to identify cross-border spread of DR variants and emerging pathogens. To achieve this, PANGenS will develop genomic epidemiology capacity across Africa by establishing a collaborative framework that brings together all expertise to perform trainings and implementation in all relevant components ranging from wet lab to bioinformatics, and establish proof-of-concept studies for TB and malaria in in selected partner countries


Funded Companies:

Company name Funding amount
Schweizerisches Tropen UND Public Health Institut ?
Centre de Recherches Medicales de Lambaréné €177,237
Forschungszentrum Borstel Leibniz Lungenzentrum €552,500
Instituto Nacional de Saúde €189,250
Koninklijke Nederlandse Centrale Vereniging TOT Bestrijding DER Tuberculose (KNCV) €187,500
Leibniz-Institut DSMZ-Deutsche Sammlung VON Mikroorganismen UND Zellkulturen GmbH €320,000
London School of Hygiene and Tropical Medicine Royal Charter €448,613
National Health Laboratory Services €275,000
Nigerian Institute OF Medical Research €171,371
THE Registered Trustees OF THE Ifakara Health Institute €178,125
Universite Nationale DES Sciences, Technologies, Ingenierie ET Mathematiques €171,213
University OF Ghana €2,150,000
University OF Namibia Unam €177,625

Source: https://cordis.europa.eu/project/id/101103174

The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: Swiss Tropical and Public Health Institute, Allschwil, Switzerland.