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EU funding (€6,799,100): The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use Hor1 Apr 2019 EU Research and Innovation programme "Horizon"

Overview

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The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use

Antimicrobial resistance (AMR) is of great public health concern, causing numerous losses of lives worldwide and threatening to reverse many of the considerable strides modern medicine has made over the last century. There is a need to stratify antibiotic and alternative treatments in terms of the actual benefit for the patient, improving patient outcome and limit the impact on AMR. High quality, effective and appropriate diagnostic tests to steer appropriate use of antibiotics are available. However, implementation of these tests into daily healthcare practice is hampered due to lack of insight in the medical, technological and health economical value and limited knowledge about psychosocial, ethical, regulatory and organisational barriers to their implementation into clinical practice. VALUE-Dx will define and understand these value indicators and barriers to adoption of diagnostics of Community-Acquired Acute Respiratory Tract Infections (CA-ARTI) in order to develop and improve health economic models to generate insight in the whole value of diagnostics and develop policy and regulatory recommendations. In addition, efficient clinical algorithms and user requirement specifications of tests will be developed fuelling the medical and technological value of CA-ARTI diagnostics. The value of diagnostics will be tested and demonstrated in a unique pan-European clinical and laboratory research infrastructure allowing for innovative adaptive trial designs to evaluate novel CA-ARTI diagnostics. Close and continuous interaction with the VALUE-Dx multi-stakeholder platform provides for optimal alignment of VALUE-Dx activities with stakeholder opinions, expert knowledge and interests. A variety of dissemination and advocacy measures will promote wide-spread adoption of clinical and cost-effective innovative diagnostics to achieve more personalized, evidence-based antibiotic prescription in order to transform clinical practice, improve patient outcomes and combat AMR.


Funded Companies:

Company name Funding amount
Abbott Rapid DX International Ltd. €0.00
ACADEMISCH ZIEKENHUIS GRONINGEN €353,972
Accelerate Diagnostics SL €0.00
BD SWITZERLAND Sàrl €0.00
Berry Consultants LLP €69,688
Bioaster Fondation de Cooperation Scientifique €63,842
Biomerieux SA €0.00
Bio-RAD €0.00
EUROPEAN RESPIRATORY SOCIETY €127,226
EUROPEAN SOCIETY CLINICAL MICROBIOLOGY INFECTIOUS DISEASES (EUROPAISCHE GESELLSCHAFT FUR KLINISCHE MIKROBIOLOGIE INFEKTIONSKRANKHEITEN) €126,508
Fondazione Penta ETS €665,349
FOUNDATION FOR INNOVATIVE NEW DIAGNOSTICS €74,930
Gesundheit Osterreich GmbH €85,190
Janssen Pharmaceutica N.V. €0.00
Luxembourg Institute OF Health €2,587.32
National Institute for Health and Care Excellence €181,631
The Chancellor, Masters and Scholars of the University of Oxford €1,584,809
THE HEALTH CORPORATION - RAMBAM €88,409
THE TRUSTEES OF BOSTON UNIVERSITY €15,053.20
The University of Edinburgh €72,916
The Wellcome Trust Ltd. €0.00
Universidad de La Rioja €154,475
Universita Degli Studi Di Verona €488,786
UNIVERSITAIR MEDISCH CENTRUM UTRECHT €1,152,248
Universitair Ziekenhuis Antwerpen €0.00
Universiteit Antwerpen €1,458,089
ZORGONDERZOEK NEDERLAND ZON €33,392

Source: https://cordis.europa.eu/project/id/820755

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