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No longer Authorized signatory (ppa) (3) · Authorized signatory (ppa) (1) Shab9 Jul 2019 Swiss Official Gazette of Commerce, Switzerland (04/07/2019)

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Novartis AG, in Basel, CHE-103.867.266, Aktiengesellschaft (SHAB Nr. 91 vom 13.05.2019, Publ. 1004628495). Ausgeschiedene Personen und erloschene Unterschriften: ?????, ?????????????, von Estavayer, in Fribourg, mit Kollektivunterschrift zu zweien; ??????, ???????? ?????, ?????????? Staatsangehöriger, in Basel, mit Kollektivunterschrift zu zweien; ?????, ????? ?????????, ???????????? Staatsangehörige, in Basel, mit Kollektivunterschrift zu zweien. Eingetragene Personen neu oder mutierend: Retzler, Dr. Charlotte, ???????? Staatsangehörige, in Lörrach (DE), mit Kollektivunterschrift zu zweien.

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The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: Novartis AG, Basle, Switzerland.

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