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EU funding (€4,999,568): HPC/Exascale Centre of Excellence in Personalised Medicine - PerMedCoE Hor14 Aug 2020 EU Research and Innovation programme "Horizon"

Overview

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HPC/Exascale Centre of Excellence in Personalised Medicine - PerMedCoE

Personalised Medicine (PerMed) opens unexplored frontiers to treat diseases at the individual level combining clinical and omics information. However, the performances of the current simulation software are still insufficient to tackle medical problems such as tumour evolution or patient-specific treatments. The challenge is to develop a sustainable roadmap to scale-up the essential software for the cell-level simulation to the new European HPC/Exascale systems. Simulation of cellular mechanistic models are essential for the translation of omic data to medical relevant actions and these should be accessible to the end-users in the appropriate environment of the PerMed-specific big confidential data. The goal of the HPC/Exascale Centre of Excellence in Personalised Medicine (PerMedCoE) is to provide an efficient and sustainable entry point to the HPC/Exascale-upgraded methodology to translate omics analyses into actionable models of cellular functions of medical relevance. It will accomplish so by 1) optimising four core applications for cell-level simulations to the new pre-exascale platforms; 2) integrating PerMed into the new European HPC/Exascale ecosystem, by offering access to HPC/Exascale-adapted and optimised software; 3) running a comprehensive set of PerMed use cases; & 4) building the basis for the sustainability of the PerMedCoE by coordinating PerMed and HPC communities, and reaching out to industrial and academic end-users, with use cases, training, expertise, and best practices. The PerMedCoE cell-level simulations will fill the gap between the molecular- and organ-level simulations from the CompBioMed and BioExcel CoEs with which this proposal is aligned at different levels. It will connect methods’ developers with HPC, HTC and HPDA experts (at POP and HiDALGO CoEs). Finally, the PerMedCoE will work with biomedical consortia (i.e. ELIXIR, LifeTime initiative) and pre-exascale infrastructures (BSC and CSC), including a substantial co-design effort.


Funded Companies:

Company name Funding amount
Atos IT Solutions And Services Iberia SL €0.00
Atos Spain SA €420,404
Barcelona Supercomputing Center Centro Nacional de Supercomputacion €1,188,774
CSC-Tieteen Tietotekniikan Keskus Oy €509,900
Elem Biotech SL €104,375
European Molecular Biology Laboratory €378,974
Fundacio Centre de Regulacio Genomica €122,500
Fundacio Institut de Recerca Biomedica (Irb Barcelona) €0.00
Institut Curie €508,750
Kungliga Tekniska Hoegskolan €299,875
Max Delbrueck Centrum Fuer Molekulare Medizin IN DER Helmholtz-Gemeinschaft (MDC) €149,425
Universitatsklinikum Heidelberg €473,500
Universite Du Luxembourg €739,840
Univerza V Ljubljani €103,250

Source: https://cordis.europa.eu/project/id/951773

The filing refers to a past date, and does not necessarily reflect the current state.