| Abstract |
Fluorescence is a sensitive tool for analytical and imaging techniques ranging from single molecule detection, ligand binding assays to cellular and in vivo imaging. These techniques rely on application and development of fluorescence probes, e.g. fluorescent dyes, proteins and quantum dots. Development and deployment of these probes requires quantitative characterisation by time resolved fluorescent spectroscopy. Recent advances in laser technology and electronics brought about a step change in instrumentation. In order to harness this new potential in our research, which encompasses engineering of quantum dots for biomedical imaging, design of biosensors for pathogen detection and use of fluorescence probes in elucidating mechanisms of molecular machines, we propose to acquire a state of the art instrument and provide training and technical assistance to a wide community of users |