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UK funding (£1,073,860): High Throughput Tools for Mammilian CellCulture Bioprocessing and Analysis Ukri 1 Apr 2006 UK Research and Innovation, United Kingdom

Overview

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High Throughput Tools for Mammilian CellCulture Bioprocessing and Analysis

Abstract The project seeks to design and build a flexible robotic platform to automate incubation and processing of hundreds of mammalian cell cultures growing in shake flasks, with integrated cell growth and metabolite analysis. Shake flasks model larger scale bioreactors, have ample volume for frequent sampling for analysis and support process development and cell line stability studies. The goal is to ensure consistent, reproducible cell processing for high throughput bioprocess research. This would facilitate systematic, parallel investigation of multiple parameters influencing cell growth or productivity, e.g. media formulation or feed regime. "Smart" software would be developed to model the process and mimic the culture expert, and thus automatically decide how and when to process each individual culture e.g. subculture to a target cell count, or when to feed to maintain a set glucose level.
Category Collaborative R&D
Reference 100047
Status Closed
Funded period start 01/04/2006
Funded period end 31/12/2008
Funded value £1,073,860.00
Source https://gtr.ukri.org/projects?ref=100047

Participating Organisations

MERCK CHEMICALS LTD
THE AUTOMATION PARTNERSHIP (CAMBRIDGE) LIMITED

£1,073,860.00

The filing refers to a past date, and does not necessarily reflect the current state. The latest known state is available on the following page: Merck Life Science UK Ltd., Gillingham.