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No longer Authorized signatory (ppa) (3) · Managing Director (3) · No longer Managing Director (2) Hrb 7 Apr 2010 German Trade Register Announcements, Germany (30/03/2010)

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Nycomed GmbH,
Unnamed street ??, 78467 Konstanz, Germany
. Appointed a.s. Managing Director: Dr. ?????????, ???????, Frauenfeld (Switzerland), *??.??.????; ?????????, ??????, chisels, *??.??.????; Dr. ?????????, ??????, Gottmadingen, *??.??.????. No longer Managing Director: Dr. ???????, ????????, Reichenau, *??.??.????; Dr. ??????, ??????, Zurich (Switzerland), *??.??.????. Procura terminated: Dr. ?????????, ???????, Frauenfeld (Switzerland), *??.??.????; ?????????, ??????, chisels, *??.??.????; Dr. ?????????, ??????, Gottmadingen, *??.??.????.

This filing was translated from German to English. The filing refers to a past date, and does not necessarily reflect the current state. The latest known state is available on the following page: Takeda GmbH, Konstanz, Germany.