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No longer Member of the board (1) · No longer Authorized signatory (ppa) (2) Shab21 Apr 2021 Swiss Official Gazette of Commerce, Switzerland (16/04/2021)

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Novartis AG, in Basel, CHE-103.867.266, Aktiengesellschaft (SHAB Nr. 65 vom 06.04.2021, Publ. 1005141024). Ausgeschiedene Personen und erloschene Unterschriften: ???????, ??????? ?????, ????????????? Staatsangehörige, in Basel, Mitglied der Geschäftsleitung, mit Kollektivunterschrift zu zweien; ????, ?????????, ?????????????? Staatsangehöriger, in Reinach (BL), mit Kollektivunterschrift zu zweien.

The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: Novartis AG, Basle, Switzerland.

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