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UK funding (£179,112): To investigate the molecular pathogenesis of aUPD in Follicular Lymphoma. Ukri1 Oct 2006 UK Research and Innovation, United Kingdom

Overview

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To investigate the molecular pathogenesis of aUPD in Follicular Lymphoma.

Abstract Cancer can be viewed as a genetic disease resulting from the accumulation of chromosomal damage within a cell. A tumour‘s subsequent clinical behaviour (for example the age of onset, aggressiveness, responsiveness to treatment and overall outcome or length of survival) will reflect the pattern of these genetic abnormalities. The clinical course and long median survival of Follicular Lymphoma provides a unique opportunity to profile these genetic events in sequential biopsy material with a view to follow the changing molecular and clinical face of this disease over time. By correlating these events with clinical behaviour we have the possibility to predict for poor prognostic patients and treat these patients more aggressively at an earlier stage of their disease. These genetic events also represent therapeutic targets so that patient treatment can be individualised and directed at a patient specific abnormality.
Category Fellowship
Reference G0600467/1
Status Closed
Funded period start 01/10/2006
Funded period end 31/03/2009
Funded value £179,112.00
Source https://gtr.ukri.org/projects?ref=G0600467%2F1

Participating Organisations

Queen Mary University of London

The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: Queen Mary University of London, London.

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