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Managing Director (3) · Share­holder agreement · Proxy · Corporate Purpose · Sub­sidiary Hrb14 Dec 2007 German Trade Register Announcements, Germany (13/12/2007)

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Insight Agents GmbH, Heidelberg (Ungenannte Str. ??, 69115 Heidelberg, Germany). The shareholders meeting of October 2, 2007 decided to amend the company agreement in Sections 2 (object), 6 (management), 13 (announcements). Subject changed, now: the research, development, authorisation and distribution of pharmaceutical and veterinary products, namely diagnostic agents (X-ray, MRI, ultrasonic contrast agents, radiopharmaceuticals) for medical purposes as a pharmaceutical entrepreneur, in compliance with legal requirements. This includes the manufacture of medicinal products exclusively as wholesalers for the transfer, packaging and labelling of medicinal products in the same form, with the exception of packages intended for delivery to the consumer. The aim is also: - the development, provision and distribution of general systems and services in the healthcare sector, in particular in connection with the management and operation of medical practices and hospital departments, - the provision of cross-practice services for the networking of practices and hospital departments, - the development, distribution and service of practical and networking software as well as internet services of all kinds, - the trade in products, facilities, services and equipment in particular in the health sector. The Company is entitled to carry out all activities necessary for the purpose of achieving the aforementioned object of the company, in particular the conduct of specialist seminars and colloquia for medical professionals and medical specialists, and to establish branches. It may participate in undertakings with similar subject-matter. General representation rules changed, well: If only one managing director is appointed, he represents alone. If several managing directors have been appointed, two represent jointly or one managing director with one authorized representative. Individual power of representation may be granted. Representation of ex officio corrected with Managing Director: Dr. ???????????????, ????????, Heidelberg, *??.??.????, authorized to represent individual. Appointed a.s. Managing Director: Dr. Welbergen, Philip, Riedstadt-Erfelden, *??.??.????; ???????, ??????, Vienna/ Austria, *??.??.????, each with individual representatives.

This filing was translated from German to English. The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: DH Healthcare GmbH, Bonn, Germany.

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