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UK funding (£64,021): Follow On: Novel Libraries of Building Blocks for Combinatorial Drug Discovery Ukri27 Sept 2006 UK Research and Innovation, United Kingdom
Overview
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Follow On: Novel Libraries of Building Blocks for Combinatorial Drug Discovery
| Abstract | Hydantoins and their derivatives have many pharmaceutical and agrochemical applications. We have invented a simple, one-step method to an important subclass of these compounds, namely 5,5-disubstituted hydantoins. Chemical libraries of this type are rather inaccessible and appear underrepresented in commercial compound collections. Hence, there is scope to produce and market them to these industries. To develop this business opportunity, we must first establish if highthroughput techniques can be applied so that many saleable compounds can be made quickly and cheaply. Herein, we will explore both parallel synthesis methods and microwave acceleration. This project will also investigate the conversion of hydantoins into other important building blocks such as a,a-disubstituted a-amino acids. We aim to establish a company to exploit this technology and the work funded herein will produce the vital results needed to secure seedcorn funding and establish a sustainable business. |
| Category | Research Grant |
| Reference | EP/E501184/1 |
| Status | Closed |
| Funded period start | 27/09/2006 |
| Funded period end | 26/07/2007 |
| Funded value | £64,021.00 |
| Source | https://gtr.ukri.org/projects?ref=EP%2FE501184%2F1 |
Participating Organisations
| University of Warwick |
The filing refers to a past date, and does not necessarily reflect the current state. The current state is available on the following page: University of Warwick, Coventry.
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